Basic Information
VIS ID
TVIS44030448
Fusion event
HTLV-1-ANO1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
69670707/70146953 (Hg38)
End
69670707/70146953 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H ; FRA11A
Target gene
ANO1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-381-3p
Nearest miRNA
hsa-mir-10392/Upstream/1063695; hsa-let-7a-2/Downstream/137002;
Nearest TSS
ENST00000527297/Upstream/5359; ENST00000529636/Downstream/18409;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/58850, chr11-CpG: 18/Downstream/8694
Upstream sequence
agactcagcaagtgtgctcttccaccttcccctgcctgctttttctagccacactggcagcagaggggatggtgcccacccagatgaagggtgggtctgc
Downstream sequence
ctctccccctccactgactcaaatgttaatctcctgtagcaacaccttcacagacacacccagaaacaacactttgcatccttcaatccaatcaagttga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate