Basic Information
VIS ID
TVIS44030456
Fusion event
HTLV-1-GAS2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
NCBI36/hg18
Start
22657425/22679303 (Hg38)
End
22657425/22679303 (Hg38)
Orient
-
Location type
Intronic
Target gene
GAS2
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-210/Upstream/2919220; hsa-let-7a-2/Downstream/739802;
Nearest TSS
ENST00000527297/Upstream/4530; ENST00000526665/Downstream/76345;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/12232, chr11-CpG: 60/Downstream/149916
Upstream sequence
AGTTTTGTGACCAACATTCAAAAAAGACAGCAAAACAGTCATGAAGATCTTATCGTCTTTCTTTACAAAAAGTTTATTTAGCCATTGTTGCCTATTGTAC
Downstream sequence
ATTAAATATACACATTTCATTTTTATTTTAGATCTTTTGTTATTTTTGCTCATGAACCAAATATTGCCAATTTGTTATTTAACTATGCCCTTAGGGTATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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