Basic Information
VIS ID
TVIS44030470
Fusion event
HTLV-1-TANGO6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
67608839/69017435 (Hg38)
End
67608839/69017435 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
TANGO6
miRNAs that regulate target gene
hsa-mir-320b ; hsa-mir-193b-3p ; hsa-mir-15b-5p ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-1225/Upstream/783936; hsa-mir-11401/Downstream/548373;
Nearest TSS
ENST00000527434/Upstream/43563; ENST00000561931/Downstream/9140;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/173521, chr16-CpG: 203/Downstream/88290
Upstream sequence
tagtacacacttaatcattatttgataagttaatATGCCTTTTCTTTATCATTTATTTTTAACTATAAGCCACTATATTAGTAAACATTAAAATGTTTCT
Downstream sequence
CCTGTGTTCTTACCCTTTTCAACCTGCAATTTCCCCTGCTTGTAGATTCCAAACTTCCTTCATTTTTTATGTGCCTTCCTTCCTGACAAGGAACCTTCTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate