Basic Information
VIS ID
TVIS44030472
Fusion event
HTLV-1-CAMK4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
110600879/111237282 (Hg38)
End
110600879/111237282 (Hg38)
Orient
+
Location type
Intronic
Target gene
CAMK4
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-185-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6509-3p ; hsa-mir-196a-3p ; hsa-mir-3128 ; hsa-mir-4746-5p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-6807-5p ; hsa-mir-922 ; hsa-mir-1245b-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6867-5p ; hsa-mir-622 ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-3156-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-3605-5p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4301 ; hsa-mir-329-5p ; hsa-mir-5197-3p
Nearest miRNA
hsa-mir-10397/Upstream/723367; hsa-mir-103a-1/Downstream/5018461;
Nearest TSS
ENST00000502646/Upstream/12818; ENST00000505763/Downstream/32807;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/12534, chr5-CpG: 51/Downstream/274840
Upstream sequence
CATGGGGTTTCCACAATTGAAACTCCTTTTGAACCCAGGGAGCTCTGGTCTTTTGTCAGTCATCTCTATCTTAAAGAGCCCCCATCTCTAAGTGATCAGG
Downstream sequence
GATACTGTCACCTTCTGTGAGGAGATTATCTACCTCTAAGATCCCTTCTAGTCCCAACCATGTGTGCACCTGCGTTTTCTTCCAGTTGAATTCTCTGGGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate