Basic Information
VIS ID
TVIS44030475
Fusion event
HTLV-1-PPP1R16A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
145681127/144484936 (Hg38)
End
145681127/144484936 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
PPP1R16A
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-10400/Upstream/22397; hsa-mir-6850/Downstream/306995;
Nearest TSS
ENST00000518652/Upstream/6585; ENST00000533829/Downstream/5094;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6417, chr8-CpG: 111/Downstream/15141
Upstream sequence
AGGGCTTTAGCCAGGCAGCTGTTACTGAGGTAAATAATGATTTGTGTTTGTAGATAAAAAATAGTGGAATAGTTTCAATTTCATATGGTTCTGCTGCTGG
Downstream sequence
GTGTTATGCAGGGGGAATCTGAGGAGCACTGAGATCACTGGGAAAGAggccgggtgcgtggctcacgcctgtcatcccagcacttcgggaggccgaggca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate