Basic Information
VIS ID
TVIS44030477
Fusion event
HTLV-1-DOCK9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
NCBI36/hg18
Start
98445158/98994903 (Hg38)
End
98445158/98994903 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
DOCK9
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-32-5p ; hsa-mir-16-5p ; hsa-mir-214-3p ; hsa-mir-218-5p ; hsa-mir-4477a ; hsa-mir-889-3p ; hsa-mir-1295b-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-1277-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1297/Upstream/786303; hsa-mir-1267/Downstream/361228;
Nearest TSS
ENST00000623511/Upstream/16819; ENST00000562781/Downstream/20877;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/242054, chr13-CpG: 222/Downstream/91174
Upstream sequence
TGACTTCTACAAAAAAATTAAGAACATATATATGGTAACCAATTCTTTGTGTCaaatatataattattacatattaaaatattCTAGAAGCTCAAAAATA
Downstream sequence
TTAAACACTTAAGTTTTACTTTTCTGTTCACTTTAAATTGTAAACGAGTGAAAAATTCTAAGTTCGTGAGGTATGGTTATTACCCTTTGACAAACAGGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate