Basic Information
VIS ID
TVIS44030492
Fusion event
HTLV-1-COMMD10 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
115760826/116397230 (Hg38)
End
115760826/116397230 (Hg38)
Orient
+
Location type
Intronic
Target gene
COMMD10
miRNAs that regulate target gene
hsa-mir-16-5p
Nearest miRNA
hsa-mir-10397/Upstream/141396; hsa-mir-103a-1/Downstream/2577356;
Nearest TSS
ENST00000502646/Upstream/93096; ENST00000512128/Downstream/50317;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/35338, chr5-CpG: 27/Downstream/50149
Upstream sequence
TCCGGCTTCTTTCTCAGCCACCTCTGTGACCACCTGCTTAAATGTATATTCCTCCCGAGGACTGCCCAGCTGCTTTTTGGAAGAGCCCCCACTTTGCTCA
Downstream sequence
GCTCCCACAGCACCCCATACCTCCCTCAAAACATGCACGTTAGTAAAGTTCTTGCTTCAGAATTGAAAGGTGCTTCCACATTTGAGCTTCAAAATGGACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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