Basic Information
VIS ID
TVIS44030493
Fusion event
HTLV-1-SENP6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
NCBI36/hg18
Start
76395834/75629398 (Hg38)
End
76395834/75629398 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
SENP6
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-640 ; hsa-mir-510-3p ; hsa-mir-488-3p ; hsa-mir-5696 ; hsa-mir-5701 ; hsa-mir-4796-5p ; hsa-mir-1284 ; hsa-mir-4729
Nearest miRNA
hsa-mir-10398/Upstream/200925; hsa-mir-10524/Downstream/2909865;
Nearest TSS
ENST00000381078/Upstream/8735; ENST00000487548/Downstream/4252;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/26551, chr6-CpG: 104/Downstream/119322
Upstream sequence
ttttttatttttattttttttgagacagagtctcctggcccccaggcaggagtgcagtggcgcaatcttggctcactgcaaccttcgccttcccaggttc
Downstream sequence
aagcaattctcttgcctcagcctcctgagtagctgggactacaggcgtatgccaccatgtctggctagtttttgtgtttttaacagagacaaggtttcac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate