Basic Information
VIS ID
TVIS44030522
Fusion event
HTLV-1-AKR1E2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
NCBI36/hg18
Start
4877642/4845450 (Hg38)
End
4877642/4845450 (Hg38)
Orient
+
Location type
Intronic
Target gene
AKR1E2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-5699/Upstream/854191; hsa-mir-107/Downstream/1306746;
Nearest TSS
ENST00000439456/Upstream/5666; ENST00000476100/Downstream/117803;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/18845, chr10-CpG: 54/Downstream/567018
Upstream sequence
ggaaggggctcccacagtgcaacggtgggctgaagggctcctcaagtgccgccaaagtgggagcccaggcagaggaggcccggagagctagtgagggttg
Downstream sequence
tgagggctgccagcatgctgtcacccctcaATGGGGGCTGCCAGCATGCTGTCACCCCTCAATGGGGGCCTGGCCTAAGGTGCCCTCTGTGCCCTGCAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate