Basic Information
VIS ID
TVIS44030581
Fusion event
HTLV-1-LARGE1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
32268466/33542480 (Hg38)
End
32268466/33542480 (Hg38)
Orient
+
Location type
Intronic
Target gene
LARGE1
miRNAs that regulate target gene
hsa-mir-18a-5p
Nearest miRNA
hsa-mir-1286/Upstream/105811; hsa-let-7a-3/Downstream/1793160;
Nearest TSS
ENST00000624155/Upstream/158253; ENST00000610170/Downstream/22539;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/484012, chr22-CpG: 20/Downstream/107888
Upstream sequence
CTCCATTCCTGCCTTGGACAGTGTTTCATGCCGGATATAAACTCAGTGACTCAAGTCCCCTTGGTGACTTCAGGGTCCCTCTTATTTGCTCCTTTAAAGG
Downstream sequence
AACAGAAGGGAGAAAAATATATCGTAGAATCCAAAGAGCCCAGAGGCCAGAGACCTAATTTTGTTTATTCAATAACTAATATTTTAGTATCTAGTAGGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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