Basic Information
VIS ID
TVIS44030596
Fusion event
HTLV-1-BNC2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
NCBI36/hg18
Start
16565884/16575886 (Hg38)
End
16565884/16575886 (Hg38)
Orient
+
Location type
Intronic
Target gene
BNC2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-629-3p ; hsa-mir-3973 ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-8064 ; hsa-mir-892a ; hsa-mir-297 ; hsa-mir-4666b ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-455-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4499 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-2278 ; hsa-mir-561-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-17-3p ; hsa-mir-545-5p ; hsa-mir-410-3p ; hsa-mir-6867-3p ; hsa-mir-516a-5p ; hsa-mir-4713-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6740-3p ; hsa-mir-942-5p ; hsa-mir-1264 ; hsa-mir-510-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4315 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3691-3p ; hsa-mir-3908 ; hsa-mir-568
Nearest miRNA
hsa-mir-101-2/Upstream/10567982; hsa-let-7a-1/Downstream/1997420;
Nearest TSS
ENST00000422679/Upstream/102698; ENST00000439447/Downstream/49790;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1022550, chr9-CpG: 30/Downstream/150975
Upstream sequence
CTCATGGAGAGACCAGAATCCAGCTGCCTCACCAAAACTAGGAGGCAGCTAAAAGCTGTTTTCCCTGAGCAAAAGAGAATTTTGCAGCTAGGCAAAGCCG
Downstream sequence
GGTTTCAGCATTTACAATCTGGAAAAACTAAGTCCACTAGAAAGACAAATTCTTTAAGCAGATACTGCACCAGCTTCCGCTTTTTCCAAACGAGTGCACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate