Basic Information
VIS ID
TVIS44030606
Fusion event
HTLV-1-THSD4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
NCBI36/hg18
Start
69322918/71243525 (Hg38)
End
69322918/71243525 (Hg38)
Orient
-
Location type
Intronic
Target gene
THSD4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-1909-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-6768-3p ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-4665-5p ; hsa-mir-4472 ; hsa-mir-1275 ; hsa-mir-4447 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-7160-5p ; hsa-mir-6853-5p ; hsa-mir-6087 ; hsa-mir-4649-3p ; hsa-mir-1827 ; hsa-mir-670-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-6882-3p ; hsa-mir-1908-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4312 ; hsa-mir-637 ; hsa-mir-6852-5p ; hsa-mir-6791-5p ; hsa-mir-4308 ; hsa-mir-4292 ; hsa-mir-4438 ; hsa-mir-3925-3p ; hsa-mir-4709-3p ; hsa-mir-665 ; hsa-mir-6863 ; hsa-mir-766-3p ; hsa-mir-873-5p
Nearest miRNA
hsa-mir-10393/Upstream/1164057; hsa-mir-11181/Downstream/1343692;
Nearest TSS
ENST00000557528/Upstream/54483; ENST00000567776/Downstream/303703;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/28168, chr15-CpG: 18/Downstream/568326
Upstream sequence
ctcaagtgcaatatatAAGTTTCCCAGAGGTTCTCTGCTATTCCAGGTGTAAACACTAGGTATTGTAGCATGAAGAAGTCTGAGAGTGAAGTTGTGAAGA
Downstream sequence
GTCTTCTCTTAGGGGAAGAGCTGGGACAGCTAAGGTGATAGATGGCACACAGAGGCCTCTGGGCAGCAGTAAGTTCCTAACTGGTGTGGAAGTATGTTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate