Basic Information
VIS ID
TVIS44030638
Fusion event
HTLV-1-OSBPL1A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
20156993/24323031 (Hg38)
End
20156993/24323031 (Hg38)
Orient
-
Location type
Intronic
Target gene
OSBPL1A
miRNAs that regulate target gene
hsa-mir-340-5p ; hsa-mir-146a-5p ; hsa-mir-21-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-6731-3p ; hsa-mir-4301 ; hsa-mir-6777-3p ; hsa-mir-3938 ; hsa-mir-7844-5p ; hsa-mir-5003-3p
Nearest miRNA
hsa-mir-1-2/Upstream/1285; hsa-mir-122/Downstream/2268436;
Nearest TSS
ENST00000575820/Upstream/11499; ENST00000579347/Downstream/41756;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/50826, chr18-CpG: 75/Downstream/74280
Upstream sequence
AGGAATGATGTAATATTTAAAAGTTTGCATGACACAGATTtgtcccttaatgggaaaatttaataaagatgccaattctccttaaattaatttacataga
Downstream sequence
atgtaatttcaattaaatcccaatgaagagcctcagaaaattattttAAATGCCTTCTGGAAGAATAAACAGATAAGGATGTCAAAGAAAATCCTTAAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate