Basic Information
VIS ID
TVIS44030640
Fusion event
HTLV-1-PHACTR3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
57742646/59734196 (Hg38)
End
57742646/59734196 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHACTR3
miRNAs that regulate target gene
hsa-mir-3181
Nearest miRNA
hsa-mir-103a-2/Upstream/915883; hsa-mir-1-1/Downstream/574278;
Nearest TSS
ENST00000382410/Upstream/12986; ENST00000492611/Downstream/101657;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/128464, chr20-CpG: 184/Downstream/198504
Upstream sequence
GGTCAGGTCCCCACACGCCTTCCTAAGCTCACCTATGTCAACTCTGTTCCATAGACCATAAGCTCCAGCCTAAGGGTCCTCAAGTTCCAGTGCACAGACC
Downstream sequence
CACACCAGCAAATTAAGAACACTAAGAGCAATGCAGTTGGGTTTTCATTTACGAATGTAGAATCAATTAAtttttttaagagacagggtcttgctctgtt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate