Basic Information
VIS ID
TVIS44030641
Fusion event
HTLV-1-MAP3K7CL integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
29399602/29105410 (Hg38)
End
29399602/29105410 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAP3K7CL
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7c/Upstream/2151367; hsa-mir-3197/Downstream/1269884;
Nearest TSS
ENST00000624081/Upstream/13156; ENST00000451489/Downstream/3722;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/31476, chr21-CpG: 137/Downstream/193013
Upstream sequence
ATGCTGATGATTAACATTCAACAGATCTGATTCTGCCCTGCCTTCTTCCTGTTGCTCATTCCACTGAGCCTCTCGAGCTCTGAGCTGAAAACCAAGATGA
Downstream sequence
TAAGGATGAGGTCTTTGGCCTCAGGGAGGAGCTTCCTGCTTAGTTATCCAGTTATACCTATAAAGGAATAATCCTAGTACTGTGTGATTAATGATCTAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate