Basic Information
VIS ID
TVIS44030643
Fusion event
HTLV-1-RTCB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
31116896/32390909 (Hg38)
End
31116896/32390909 (Hg38)
Orient
+
Location type
Intronic
Target gene
RTCB
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-423-3p ; hsa-mir-92a-3p ; hsa-mir-1262 ; hsa-mir-152-5p ; hsa-mir-182-3p ; hsa-mir-29b-1-5p ; hsa-mir-3157-5p ; hsa-mir-3692-5p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4252 ; hsa-mir-4264 ; hsa-mir-4290 ; hsa-mir-4701-3p ; hsa-mir-542-3p ; hsa-mir-597-3p ; hsa-mir-6071 ; hsa-mir-616-5p ; hsa-mir-622 ; hsa-mir-661 ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6764-3p ; hsa-mir-6776-5p ; hsa-mir-6824-3p ; hsa-mir-6828-3p ; hsa-mir-6884-3p ; hsa-mir-6889-3p ; hsa-mir-93-3p
Nearest miRNA
hsa-mir-1286/Upstream/769378; hsa-let-7a-3/Downstream/1045673;
Nearest TSS
ENST00000624155/Upstream/7123; ENST00000465418/Downstream/9076;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/214371, chr22-CpG: 36/Downstream/20929
Upstream sequence
TATTAAAAAAAATAAGTCTTTGTCATACTCTGACTCAGTAATTCCACtttttttccttatttttttttagagatagggtcttgctttgcaccaagtctgg
Downstream sequence
acaatcacatagcttactgtaacctcaaggtcctgggctcaagcaatcctccagcttcagtctcctgagttgctaggactacacctggctaatctttggc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate