Basic Information
VIS ID
TVIS44030651
Fusion event
HTLV-1-DOCK10 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q36.2
Reference genome
NCBI36/hg18
Start
225390651/224817690 (Hg38)
End
225390651/224817690 (Hg38)
Orient
+
Location type
Intronic
Target gene
DOCK10
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10b/Upstream/4911125; hsa-mir-1244-1/Downstream/192771;
Nearest TSS
ENST00000437798/Upstream/1038; ENST00000636099/Downstream/22515;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/231919, chr2-CpG: 114/Downstream/224246
Upstream sequence
TATATGTTAACTATTTTACATTGAGAACATTCTGTTTGGTCTTTGAAAATACATAATTTAGGTCTGCTGCAATTAAATGGATATTCTGCAAATTTCATGC
Downstream sequence
ATGACAGGAGCACAAATGAAGAATATACTTTCAAAAAAAATTGAGAGAGAGAATTGGATtttcaaaaccagatgacataaaatcatgtaactcctctggt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate