Basic Information
VIS ID
TVIS44030676
Fusion event
HTLV-1-SV2C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
75599124/76267543 (Hg38)
End
75599124/76267543 (Hg38)
Orient
+
Location type
Intronic
Target gene
SV2C
miRNAs that regulate target gene
hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-517-5p ; hsa-mir-520g-5p ; hsa-mir-3613-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p
Nearest miRNA
hsa-mir-10397/Upstream/3388880; hsa-mir-103a-1/Downstream/6572612;
Nearest TSS
ENST00000502646/Upstream/183357; ENST00000506257/Downstream/24222;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/93195, chr5-CpG: 133/Downstream/135391
Upstream sequence
GATGGCCTGTACCTTTCATGCCTTTTTAACTGTGGAGGGTATATCAAAATGTAAAGTATTCTTTTGTATATTCCATTCTACTTAAGGTGATTCAAACAGG
Downstream sequence
TTAAATTTTTCAGTCTCTGGAATTTAGCAGGATTTAGCAGAGTATATATTATAAACAAATATGTAGAACAGGTGATACATGCTGGGAGAGTGGTTGTCTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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