Basic Information
VIS ID
TVIS44030686
Fusion event
HTLV-1-OGFOD1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
NCBI36/hg18
Start
55056876/56465463 (Hg38)
End
55056876/56465463 (Hg38)
Orient
-
Location type
Intronic
Target gene
OGFOD1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-615-3p ; hsa-mir-222-3p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-5571-5p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-939-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p
Nearest miRNA
hsa-mir-1225/Upstream/219840; hsa-mir-11401/Downstream/393055;
Nearest TSS
ENST00000527434/Upstream/7334; ENST00000219162/Downstream/699;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/13601, chr16-CpG: 59/Downstream/54154
Upstream sequence
gagttccaattgaacaccacagggttcattctagatttctgcatttccatatttgtaactcccttcttgaacagtgagaaacctggcttccattatcttc
Downstream sequence
aatgtatttatctattgaaacaatccCTCCATGTGTAATTGGTTGCAGTTCACCATAGCCTTCCCTCCCTCTCAGCCTGCACAGATGCCTATCTTGCTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate