Basic Information
VIS ID
TVIS44030706
Fusion event
HTLV-1-FLI1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
128110156/128735051 (Hg38)
End
128110156/128735051 (Hg38)
Orient
+
Location type
Intronic
Target gene
FLI1
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-124-3p
Nearest miRNA
hsa-let-7a-2/Upstream/212602; hsa-mir-4697/Downstream/1931684;
Nearest TSS
ENST00000527297/Upstream/39028; ENST00000608055/Downstream/23055;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/39881, chr11-CpG: 16/Downstream/75386
Nearest cancer related gene
FLI1(OG, No orient, 0)
Upstream sequence
AGCTgagaaagtgcagcctcgtggaaagggccccacggaagggagtccagagggttggcctcacactcttccccttcccgctttatgaccacgaacgtag
Downstream sequence
tccttcagaacctttgtttcttcatcagcaaagtgggggaggggaataatcctgccttcttctccagtttattagagtaattaaataagattatagatgt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate