Basic Information
VIS ID
TVIS44030733
Fusion event
HTLV-1-ZZEF1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
3972176/4122133 (Hg38)
End
3972176/4122133 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZZEF1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-125a-5p ; hsa-mir-16-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1253/Upstream/1373951; hsa-mir-10226/Downstream/847569;
Nearest TSS
ENST00000595228/Upstream/46953; ENST00000577075/Downstream/20887;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/117050, chr17-CpG: 78/Downstream/20365
Upstream sequence
ATTAATGTATGGAAACTATCCTTCCCTAGCTCAATACGTCACTCAGCAGTGAGTAAGCTAGAGGGTCAAGAGCAATCAGATTTACATTTATGTGTCTATC
Downstream sequence
AAATCTATTTTGCCTCCATTGCTGCCCTAGTGACCCTAAGTATTATGACACCAAGTGCACAGAGCAGGAAAAACGCTGAGGTAAAGTAAACCAAGACCGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate