Basic Information
VIS ID
TVIS44030738
Fusion event
HTLV-1-DYNC1I1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
95325781/95858533 (Hg38)
End
95325781/95858533 (Hg38)
Orient
-
Location type
Intronic
Target gene
DYNC1I1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10525/Upstream/2141528; hsa-mir-10399/Downstream/361129;
Nearest TSS
ENST00000635602/Upstream/20915; ENST00000497626/Downstream/174134;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/85413, chr7-CpG: 75/Downstream/462934
Upstream sequence
taagtagaaagagtacactctaaaataacaatcaaaagtatggtaaatacataaaccaatatcatagtcatttattatcattatcaaatatataatgtac
Downstream sequence
ataattatatgtactatatttttatatgactggcagtgcagtgggtttgtaaacaccaatagcaccacaaacatgtgtaatgtactgcagtatgatgtta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate