Basic Information
VIS ID
TVIS44030745
Fusion event
HTLV-1-VRK3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
55172252/49977183 (Hg38)
End
55172252/49977183 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
VRK3
Nearest miRNA
hsa-mir-10395/Upstream/44046; hsa-let-7e/Downstream/1229746;
Nearest TSS
ENST00000633603/Upstream/16011; ENST00000598809/Downstream/4001;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/47302, chr19-CpG: 100/Downstream/47736
Upstream sequence
AAGGCCTCGGGTCTTGAGAAGCAGCAGGTACATAAAGCCAGGATgaggggagctttccagaactcgggatggcaggtgcaaaggttccggggtggggtcc
Downstream sequence
agcttggcctggtctagaatcagaggggcgggggtgtggctggtgcatcgtgcacgggggaggaagGGAGCTCGGCCTCGGGCCAAGGCAAGGAGCTGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate