Basic Information
VIS ID
TVIS44030755
Fusion event
HTLV-1-ARID2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
44578533/45898483 (Hg38)
End
44578533/45898483 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARID2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-424-3p ; hsa-mir-15b-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-374a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4474-3p ; hsa-mir-222-5p ; hsa-mir-4501 ; hsa-mir-545-5p ; hsa-mir-802 ; hsa-mir-203a-3p ; hsa-mir-194-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-127-5p ; hsa-mir-6071 ; hsa-mir-7160-5p ; hsa-mir-8077 ; hsa-mir-4663 ; hsa-mir-873-3p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-4329 ; hsa-mir-6728-3p ; hsa-mir-4499 ; hsa-mir-5584-3p ; hsa-mir-4277
Nearest miRNA
hsa-mir-1244-3/Upstream/3574624; hsa-let-7i/Downstream/1289329;
Nearest TSS
ENST00000382841/Upstream/6440; ENST00000550319/Downstream/24617;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/167811, chr12-CpG: 115/Downstream/91295
Nearest cancer related gene
ARID2(TSG, No orient, 0)
Upstream sequence
gtacttaatgccactgaactgtacacttaaaagtggttaaaatagtacgttttatgttatgtatgttttaccacaatggaaaaaaACTAAAACACAACAA
Downstream sequence
AGGAAGGATTTGgggaaaattggaagtgactgctaatgggtattgggtttcttttaaagatgatgaaaatattctagaattgtggtgatggttgcacaat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate