Basic Information
VIS ID
TVIS44030758
Fusion event
HTLV-1-GATM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
43447053/45367563 (Hg38)
End
43447053/45367563 (Hg38)
Orient
-
Location type
Intronic
Target gene
GATM
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4263 ; hsa-mir-297 ; hsa-mir-6873-3p ; hsa-mir-6830-3p ; hsa-mir-567 ; hsa-mir-6845-3p ; hsa-mir-1264 ; hsa-mir-3184-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-126-5p ; hsa-mir-3677-5p ; hsa-mir-3926 ; hsa-mir-3927-3p ; hsa-mir-4257 ; hsa-mir-4458 ; hsa-mir-4460 ; hsa-mir-4480 ; hsa-mir-4500 ; hsa-mir-4727-3p ; hsa-mir-548ac ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548j-3p ; hsa-mir-548s ; hsa-mir-548x-3p ; hsa-mir-548z ; hsa-mir-6831-5p ; hsa-mir-8069 ; hsa-mir-944 ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-10393/Upstream/649670; hsa-mir-11181/Downstream/65487;
Nearest TSS
ENST00000557528/Upstream/1493; ENST00000617932/Downstream/2144;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/168509, chr15-CpG: 114/Downstream/10209
Upstream sequence
AACTCATACCATAAAACGAGATGCCATGTTTCCCCTGCCAAATTTGATTGGGAGTGGCAAAACTAATTCATTATTTATTTCTGTCTTTAAACCCAGAAGC
Downstream sequence
TATTTTGATTTTTAAATTTTTTTCTATAAAAGATCAAATGGTAACTGATTTAATAAGGGACATACATTTCATTTTACTGTGAATTTGAACTGTAGATCAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate