Basic Information
VIS ID
TVIS44030760
Fusion event
HTLV-1-MEF2A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
NCBI36/hg18
Start
97953119/99595391 (Hg38)
End
97953119/99595391 (Hg38)
Orient
+
Location type
Intronic
Target gene
MEF2A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-132-3p ; hsa-mir-21-5p ; hsa-mir-30a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10393/Upstream/810889; hsa-mir-1302-10/Downstream/2365068;
Nearest TSS
ENST00000557528/Upstream/28908; ENST00000561125/Downstream/111204;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/28531, chr15-CpG: 84/Downstream/137305
Upstream sequence
TATTATGTTaggctttccctggatgcattgtctatagttttaatctccttcctctggcagtacttccttccctgcttaatttttttttctcattaaggac
Downstream sequence
ttttccaccaacctaccacctatattatatattccttattcaccttgtactataggtctccccactagaatgtaagctctatgaagtcaggaatagggat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate