Basic Information
VIS ID
TVIS44030799
Fusion event
HTLV-1-FAM107B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
NCBI36/hg18
Start
14759248/14677243 (Hg38)
End
14759248/14677243 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM107B
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-3942-3p ; hsa-mir-759 ; hsa-mir-5197-3p ; hsa-mir-6882-5p ; hsa-mir-6507-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6507-5p ; hsa-mir-8485 ; hsa-mir-1183 ; hsa-mir-3607-3p ; hsa-mir-4311
Nearest miRNA
hsa-mir-1265/Upstream/240582; hsa-mir-107/Downstream/3167864;
Nearest TSS
ENST00000439456/Upstream/24501; ENST00000493178/Downstream/97462;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/72537, chr10-CpG: 125/Downstream/160527
Upstream sequence
attatagctgctactctccatttcccagtggcctttccaggaactcaTCAACGCAGccaaagtcatgcttctcaaaaacgacaaaaaggagattcaaacc
Downstream sequence
caggcctactcggctctcaaacccgtgatataaagcactacactaaactCTCTTCCTAATCCCAATGCCTCTCTCTTTTTAAAGCTACAGATACCTggcc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate