Basic Information
VIS ID
TVIS44030802
Fusion event
HTLV-1-SPATA13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q12.12
Reference genome
NCBI36/hg18
Start
23636428/24164289 (Hg38)
End
23636428/24164289 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPATA13
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-27a-3p ; hsa-let-7e-5p ; hsa-mir-376a-5p ; hsa-mir-382-3p ; hsa-mir-548c-3p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-513a-5p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-27b-3p ; hsa-mir-5100 ; hsa-mir-139-5p ; hsa-mir-1283 ; hsa-mir-194-3p ; hsa-mir-1288-5p ; hsa-mir-8063 ; hsa-mir-3941 ; hsa-mir-4643 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1252-5p ; hsa-mir-494-3p ; hsa-mir-651-3p ; hsa-mir-3064-3p ; hsa-mir-6861-3p ; hsa-mir-6821-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-140-3p ; hsa-mir-6800-3p ; hsa-mir-4700-3p ; hsa-mir-510-3p ; hsa-mir-203a-3p ; hsa-mir-4261 ; hsa-mir-4496 ; hsa-mir-6079 ; hsa-mir-6828-5p ; hsa-mir-671-5p
Nearest miRNA
hsa-mir-2276/Upstream/1785; hsa-mir-1267/Downstream/15499745;
Nearest TSS
ENST00000623511/Upstream/3541; ENST00000474317/Downstream/59952;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2890, chr13-CpG: 67/Downstream/143671
Upstream sequence
TGCTTACCTGATTTTCCTCATCTTTGCATCACAAATGAAAGAGCAGTAAAGGGGGAGCATAGAGTAGGTTGCTGTTTTTCTGTTGGCCTCTGCTGTACCC
Downstream sequence
ACATCCTTCTCTGGACTCCCACTGAGCCCCCTTGCTCCTGCCTCTGCTCCCTCCATGTTTAATGCCTCTTTTGGCTCCCCAGGGAACCTGCAGGGTATTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate