Basic Information
VIS ID
TVIS44030807
Fusion event
HTLV-1-ARHGAP28 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
NCBI36/hg18
Start
6869011/6879012 (Hg38)
End
6869011/6879012 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP28
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-196a-5p ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-3976/Upstream/504587; hsa-mir-1-2/Downstream/3880572;
Nearest TSS
ENST00000575820/Upstream/3988; ENST00000579796/Downstream/17748;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/148974, chr18-CpG: 27/Downstream/41580
Upstream sequence
ATCCACTAAACTACTAAAAACTCCATTATAATTATCCTCGGATTGAACCAAGTCGATGATACCAGCCCTGTGGTCCGCTAGTGTATCATTACTGTGAACG
Downstream sequence
GTCTGGCCTGGCTTTGTGCTTTAATTGCTTGGGGAGGCTGACAGGGGAGCAGCCCTGGGAGGAAGCTGCTGGTTTTAGCCAAACAGGGAACACGCAGCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate