Basic Information
VIS ID
TVIS44030832
Fusion event
HTLV-1-RERG integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
15257348/15213147 (Hg38)
End
15257348/15213147 (Hg38)
Orient
-
Location type
Intronic
Target gene
RERG
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/2297229; hsa-let-7i/Downstream/2460152;
Nearest TSS
ENST00000382841/Upstream/61224; ENST00000545023/Downstream/4482;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/409610, chr12-CpG: 49/Downstream/7905
Upstream sequence
AAGCCTTCATGGATGAGTGCACCAATTGGCTTTTGAATTACAGGATAGCATTACTCAATTAACTTTAAGACTAGCCCTTTCAAGCAATATAGTTAGCTGT
Downstream sequence
GGCACACAATATTTCAGTTCTAAAATGAGAATGTCAACTGTGAAGCTAAATTTACAATTTCAGTTGTTTCTCTATCAGCCCCCTCCCACACTTACTACAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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