Basic Information
VIS ID
TVIS44030844
Fusion event
HTLV-1-RNF13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
151045671/149845194 (Hg38)
End
151045671/149845194 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
RNF13
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-1273e ; hsa-mir-4424 ; hsa-mir-3160-3p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-4680-3p
Nearest miRNA
hsa-let-7g/Upstream/15407288; hsa-mir-1224/Downstream/1720682;
Nearest TSS
ENST00000440867/Upstream/27952; ENST00000490631/Downstream/826;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/31747, chr3-CpG: 170/Downstream/124896
Upstream sequence
AATTATTCACAGGTATTTTACTTCCAGTGTGTGAGTCAGAGATTCAGAGTTTGAGTCTATATGGCAGCTTCTATATCTAGAGCACTTATCCACACTAATC
Downstream sequence
ATCATCAAAACGGATATTACATGAGTTTGGGATATTTAATGAAATAATTCATTATAAAAGCCCTTGTTTTTGTAATGTTCGTTCTCACTTGTTTAAGAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate