Basic Information
VIS ID
TVIS44030852
Fusion event
HTLV-1-TNIP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
NCBI36/hg18
Start
150444515/151084761 (Hg38)
End
150444515/151084761 (Hg38)
Orient
+
Location type
Intronic
Target gene
TNIP1
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-324-3p ; hsa-mir-181a-5p ; hsa-mir-517a-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-885-5p ; hsa-mir-5011-5p ; hsa-mir-625-3p ; hsa-mir-582-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10397/Upstream/1351871; hsa-mir-103a-1/Downstream/437326;
Nearest TSS
ENST00000502646/Upstream/3677; ENST00000523466/Downstream/2397;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/3458, chr5-CpG: 40/Downstream/72769
Upstream sequence
ACATTCCTCATTGCATTAGGAGAATGAGTGAATCAGGGCCTTGGCTAGGGGAGAATGGAACTCGGGAGCAGCTAATGAACTAGGAAAAGAGCAGCCCTGG
Downstream sequence
GTCCCTTCCTTAGATCCATAACCTGAGGCAATCTCAGGAGTGTAAGACCCTCCAGTGGATTCTAGGTACTTTTTGGTGCTGGGTGTATGTGTATGTTAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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