Basic Information
VIS ID
TVIS44030887
Fusion event
HTLV-1-LRRTM4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
NCBI36/hg18
Start
77499715/77419081 (Hg38)
End
77499715/77419081 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LRRTM4
miRNAs that regulate target gene
hsa-mir-1305 ; hsa-mir-6868-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-205-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/2328167; hsa-mir-10b/Downstream/2230213;
Nearest TSS
ENST00000437798/Upstream/433116; ENST00000438443/Downstream/103129;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1708068, chr2-CpG: 32/Downstream/1573985
Upstream sequence
atcatgtttattgattatatgtttctgctagattataagtttcacaaaggcatttttaagtcttctttatttactcatatatattgggtacttagaatag
Downstream sequence
tacacaatatatagtagacacaataaatatttgttgcatgagtgaaCACATAAATACATTATTTTTGTCTGCCCTGTCAGTGGATTTATCTATTTATTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate