Basic Information
VIS ID
TVIS44030910
Fusion event
HTLV-1-NTRK1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
155060146/156823730 (Hg38)
End
155060146/156823730 (Hg38)
Orient
-
Location type
Intronic
Target gene
NTRK1
Nearest miRNA
hsa-mir-101-1/Upstream/403301; hsa-mir-1182/Downstream/112401;
Nearest TSS
ENST00000473358/Upstream/6868; ENST00000533630/Downstream/13479;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9485, chr1-CpG: 74/Downstream/21359
Nearest cancer related gene
NTRK1(OG, No orient, 0)
Upstream sequence
atatggctggatgttttctctccctgctaaggaatagtaccaggtatagggctcagtatcaatgtgttgcaagcaagtttggcgcttggctgtagctctg
Downstream sequence
cacctcagtgagaaggtgtccatgatcttgagcccatgaaaagccaccaagtccactatgttgatcaggccattgtgccagcactgggcatacaggtggc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate