Basic Information
VIS ID
TVIS44030916
Fusion event
HTLV-1-ZNF672 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
NCBI36/hg18
Start
247101931/248841109 (Hg38)
End
247101931/248841109 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
ZNF672
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/14666;
Nearest TSS
ENST00000473358/Upstream/1955; ENST00000417047/Downstream/13414;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1998, chr1-CpG: 145/Downstream/6255
Upstream sequence
GGGTACGATGACTGTAGTCAGAGTATTTGTATGTGCAGTGGGCAGTGCTGTGGAGGATATGATGACTGTAGTCAGAGTACTTGTATGTGCAGTGGGTAGT
Downstream sequence
GCTGTGGAGGGTACGATGACTGTAGTCAGAGTATTTGTATGCAGTGGGTAGTGCTGTGGAGGATATGATGACTGTAGTCAGGCCCTTTCCTCCAGGGACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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