Basic Information
VIS ID
TVIS44030919
Fusion event
HTLV-1-EPB41 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
NCBI36/hg18
Start
29233215/29034116 (Hg38)
End
29233215/29034116 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPB41
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-320b ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-342-3p ; hsa-mir-320a ; hsa-mir-875-3p ; hsa-mir-7703 ; hsa-mir-196a-3p ; hsa-mir-4252 ; hsa-mir-4537 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1292-3p ; hsa-mir-4267 ; hsa-mir-1273g-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-508-5p ; hsa-mir-6821-5p ; hsa-mir-4665-3p ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-1908-3p ; hsa-mir-1228-3p ; hsa-mir-6720-5p ; hsa-mir-3685 ; hsa-mir-6079 ; hsa-mir-1299 ; hsa-mir-155-3p ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-6128 ; hsa-mir-1236-3p ; hsa-mir-140-3p ; hsa-mir-6779-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-12136/Upstream/2479523; hsa-mir-101-1/Downstream/1705040;
Nearest TSS
ENST00000473358/Upstream/15757; ENST00000644470/Downstream/5302;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/118659, chr1-CpG: 384/Downstream/87071
Nearest cancer related gene
EPB41(TSG, No orient, 0)
Upstream sequence
GGCTTTTGTGTGTATATATCACCATCTGCTGGTGAATAATGGCTAATTATTTGTGCCTGCAAATTCTGGATGTGGAGCCTTAAAAATCTTGGATAGGGAT
Downstream sequence
TACCATAGAAGCATTTATTTTGTACCATAATTATTTTACCTATGCCTAGCACAGAGCAGTCAGTGTCTTCCCTTAAAATTTCAAATTCAAGAGttattca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate