Basic Information
VIS ID
TVIS44030937
Fusion event
HTLV-1-MYO3B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
170923838/170359082 (Hg38)
End
170923838/170359082 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
MYO3B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1-3p
Nearest miRNA
hsa-mir-128-1/Upstream/1776064; hsa-mir-10b/Downstream/4808551;
Nearest TSS
ENST00000437798/Upstream/7964; ENST00000469359/Downstream/48648;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/530963, chr2-CpG: 44/Downstream/352730
Upstream sequence
gagcgagagtagtcagaaaagtaaaagaataactaagagatgtagcatcactacaggcaatgaaacagaatgtttcaagaaaccagggtaatgatggtca
Downstream sequence
ttagtgacctcttgaacagagaggttgaatacaatgagaactaaaaagggaacacagaatcggcaacttaaaggcctttagggtcctttgagagagattt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate