Basic Information
VIS ID
TVIS44030950
Fusion event
HTLV-1-PECR integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
NCBI36/hg18
Start
216622986/216050018 (Hg38)
End
216622986/216050018 (Hg38)
Orient
-
Location type
Intronic
Target gene
PECR
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-6844 ; hsa-mir-551b-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p
Nearest miRNA
hsa-mir-10b/Upstream/2291859; hsa-mir-1244-1/Downstream/1850495;
Nearest TSS
ENST00000437798/Upstream/15922; ENST00000455479/Downstream/7929;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/36389, chr2-CpG: 32/Downstream/31583
Upstream sequence
TCAAAAACTGTATCCCAggccaggtgcagtggctcatgcctgtaatcccagcactttgcgagggtgaagctggaggattgtgtgagcctaggagtttgag
Downstream sequence
accagcctgggcaaaatagggagactatgtctctacaaaaaatataaaaaagaattagctgggcatggtggtacctgcctgtggtcccagctactcagga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate