Basic Information
VIS ID
TVIS44030966
Fusion event
HTLV-1-PDZRN3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
NCBI36/hg18
Start
73651975/73520134 (Hg38)
End
73651975/73520134 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDZRN3
miRNAs that regulate target gene
hsa-mir-197-3p
Nearest miRNA
hsa-let-7g/Upstream/1978045; hsa-mir-12124/Downstream/1694342;
Nearest TSS
ENST00000440867/Upstream/45502; ENST00000608743/Downstream/36804;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/135212, chr3-CpG: 151/Downstream/103945
Upstream sequence
cagccctTAAAGCAGGGgggaacacagaagagttttaagcaggcagatgacatcatcaggtttgcatatggaaagacacccctggcactctgcttagaga
Downstream sequence
agaAAGAGGTAACAGAGAGCTATATCAAACTGCTTTGTCTCCTATATATCTTTGGGGCTGCTAATTAGCTATATCAAGAGTAAACTAggccaggtgtggt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate