Basic Information
VIS ID
TVIS44030968
Fusion event
HTLV-1-EPHA6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
98870811/97669277 (Hg38)
End
98870811/97669277 (Hg38)
Orient
+
Location type
Intronic
Target gene
EPHA6
miRNAs that regulate target gene
hsa-mir-18a-3p ; hsa-mir-216b-5p ; hsa-mir-3675-3p ; hsa-mir-4290 ; hsa-mir-4667-3p ; hsa-mir-4691-5p ; hsa-mir-4762-5p ; hsa-mir-5193 ; hsa-mir-519d-5p ; hsa-mir-520f-5p ; hsa-mir-6779-3p ; hsa-mir-6792-3p
Nearest miRNA
hsa-let-7g/Upstream/1309238; hsa-mir-12124/Downstream/2295037;
Nearest TSS
ENST00000440867/Upstream/227861; ENST00000506349/Downstream/78243;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/854496, chr3-CpG: 38/Downstream/95019
Upstream sequence
ATTGTAGCAAGTCTCTAAAATACTAAGATCTTTCATATGTGTCCATTATTCTATTGTTGACCTCCTCTTTTACTTTCTGTTTTGTTTTTTTTTTCTAATA
Downstream sequence
TATATACCCATGTTATCCTTTATGTTACCTTGCATTCTCGTTTGGCTTCTCTTTTTTCATTGTGTAGATCAGTGTATCAGTAATTATCTTGCATCTCCCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate