Basic Information
VIS ID
TVIS44030975
Fusion event
HTLV-1-UBE2E2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
NCBI36/hg18
Start
23476608/23460113 (Hg38)
End
23476608/23460113 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2E2
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-149-5p
Nearest miRNA
hsa-mir-12127/Upstream/3322472; hsa-let-7g/Downstream/2204760;
Nearest TSS
ENST00000440867/Upstream/251413; ENST00000613545/Downstream/39493;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/256556, chr3-CpG: 66/Downstream/346088
Upstream sequence
TGTTTTCCAAATGAAGAATTCCTGGCAAGAAGATTAAGTGACTAAGCCGGCTGTGTACATGGCAGTGCTGGGCAGCAGCAACACAGTAGATGACACTTTC
Downstream sequence
AAGTTATTTTTATTATTTGGACCAGATGCATCTGGTTGGCACCTTGAGCCAATGAGCTGCCCTCCCAGAGGTCCTCTGGCACAGAATTGGAGTTAGTATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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