Basic Information
VIS ID
TVIS44030986
Fusion event
HTLV-1-ZNF385D integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
NCBI36/hg18
Start
21844147/21827651 (Hg38)
End
21844147/21827651 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF385D
miRNAs that regulate target gene
hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6868-3p ; hsa-mir-627-3p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-2355-5p ; hsa-mir-3124-3p ; hsa-mir-5088-3p
Nearest miRNA
hsa-mir-12127/Upstream/1690010; hsa-let-7g/Downstream/3837222;
Nearest TSS
ENST00000440867/Upstream/49875; ENST00000448980/Downstream/114915;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1641187, chr3-CpG: 86/Downstream/544350
Upstream sequence
TAAAAATCACTTGTTGAACTAAATTCACATACCAGCTAGTTCATGTTTCATCCTGATTTCATATAGGGAGGAGATTAGTAGCCACAGCATCTTACATTAA
Downstream sequence
TATATTGGAGTGCCTCTATTTTGAAGCATTACAAGGAGTCTTGGAACGTGGAAGGAAAAGGCATATTACAAAAAGAGTAATTCTCTCAGGAATTACAGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate