Basic Information
VIS ID
TVIS44030996
Fusion event
HTLV-1-FAM114A1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
NCBI36/hg18
Start
38612027/38934011 (Hg38)
End
38612027/38934011 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAM114A1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-6077 ; hsa-mir-5096 ; hsa-mir-7-5p ; hsa-mir-490-5p ; hsa-mir-192-3p ; hsa-mir-106a-3p ; hsa-mir-425-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p
Nearest miRNA
hsa-mir-12113/Upstream/65884; hsa-mir-1243/Downstream/477899;
Nearest TSS
ENST00000502981/Upstream/4912; ENST00000513966/Downstream/1721;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/65852, chr4-CpG: 93/Downstream/110555
Upstream sequence
CAAAAAGTCAGCATTAGTGTCTTTGTACTGGCGGCATTTTTCCTCACTTGTAAAGATCCGTCATCTAGTCTAGATTTCCATATCTAAGGATATAAAAATC
Downstream sequence
AAAGTTATTATAAGAACCACAGAATCCCCACCTTAATATTCCTAGAAAGAATAGGCACTTGCCTAAACATTTAGAAGGAAGAGGAAAGGACAAAGTCAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate