Basic Information
VIS ID
TVIS44031004
Fusion event
HTLV-1-PPM1K-DT integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
89437538/88297362 (Hg38)
End
89437538/88297362 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
PPM1K-DT
Nearest miRNA
hsa-mir-12113/Upstream/996779; hsa-mir-1243/Downstream/10700025;
Nearest TSS
ENST00000502981/Upstream/12420; ENST00000504905/Downstream/81377;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/12445, chr4-CpG: 29/Downstream/81476
Upstream sequence
tttatggcttgtaagccgtagtctaataagacccttgcagtcccattcacaccctcttggaatgctacagccaagacaggaggatcaggaagcccagctc
Downstream sequence
agattaacctctgtgtgaatgaaagcccacatggacagaggcccaagcatcccaatttcctagctcagctctcagctgacccaacagctggatgtaactt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate