Basic Information
VIS ID
TVIS44031030
Fusion event
HTLV-1-GRID2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
NCBI36/hg18
Start
94863262/93723088 (Hg38)
End
94863262/93723088 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
GRID2
miRNAs that regulate target gene
hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-448
Nearest miRNA
hsa-mir-12113/Upstream/6422505; hsa-mir-1243/Downstream/5274299;
Nearest TSS
ENST00000502981/Upstream/403302; ENST00000637838/Downstream/46142;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1417232, chr4-CpG: 112/Downstream/105256
Upstream sequence
TGGTAAGTGGTGTTTCTTAAACATATTTACATCTACTTACTGTTTTTATGATTTTCTCTTTGTCTGATATGACTTTCATCAATTGGATAGGGTAAGCTTC
Downstream sequence
AACACATTATTCAAAGACCAAGCCATCCTCCACTTAGCCCCTACCAGAATGAATCATGTGTTTTTCCATAGTGTTTTATACCTGTTGCTGATAGAACTTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate