Basic Information
VIS ID
TVIS44031055
Fusion event
HTLV-1-TCERG1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
NCBI36/hg18
Start
145852551/146492795 (Hg38)
End
145852551/146492795 (Hg38)
Orient
+
Location type
Intronic
Target gene
TCERG1
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-mir-769-5p ; hsa-mir-615-3p ; hsa-mir-328-3p ; hsa-mir-222-3p ; hsa-let-7a-5p ; hsa-mir-299-5p ; hsa-mir-296-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-3163 ; hsa-mir-5701 ; hsa-mir-29b-2-5p ; hsa-mir-4703-3p ; hsa-mir-5011-5p ; hsa-mir-5000-5p ; hsa-mir-410-3p ; hsa-mir-6868-3p ; hsa-mir-1283 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418
Nearest miRNA
hsa-mir-10397/Upstream/2812824; hsa-mir-103a-1/Downstream/2569518;
Nearest TSS
ENST00000502646/Upstream/11619; ENST00000505285/Downstream/74;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/44928, chr5-CpG: 97/Downstream/384988
Upstream sequence
TGCTGTTTTCTTTTGTTCTTGAAGCCTAAGTAGAGAGCTGTGTGCTTGTGTAATATCTCAGTGAAGCTTTAAAGTGAAACTTGGTATAGATTATCTGTGT
Downstream sequence
ATAATTATCTACAGTTAATATATTTTTCCTGGTATAGTTTGGACAAAGACATTGTCCAATAATTTGGTAGTTAAATTACCTATATGAAAGATTGACTTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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