Basic Information
VIS ID
TVIS44031066
Fusion event
HTLV-1-FAM172A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q15
Reference genome
NCBI36/hg18
Start
93235707/93874245 (Hg38)
End
93235707/93874245 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5B ; FRA5D
Target gene
FAM172A
miRNAs that regulate target gene
hsa-mir-421 ; hsa-mir-330-3p ; hsa-mir-218-5p ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6835-3p
Nearest miRNA
hsa-mir-10397/Upstream/253457; hsa-mir-103a-1/Downstream/2204893;
Nearest TSS
ENST00000502646/Upstream/49991; ENST00000508383/Downstream/7356;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/252611, chr5-CpG: 41/Downstream/237003
Nearest cancer related gene
FAM172A(TSG, No orient, 0)
Upstream sequence
GAGGTATTATTTTGGAACAATGTtgtactgtaatacgaaaacatatttggtctttgtccctggttcctggaacagagctcctaaaaggcttgaaagctca
Downstream sequence
tgagtcatagagtgtcttttgttattcataacaatcccctgaaaaaaatccatcactgagtttatgctaatgaggtgacttagactggggcctttagata
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate