Basic Information
VIS ID
TVIS44031067
Fusion event
HTLV-1-CTNNA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
NCBI36/hg18
Start
138122600/138759012 (Hg38)
End
138122600/138759012 (Hg38)
Orient
+
Location type
Intronic
Target gene
CTNNA1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-744-5p ; hsa-mir-296-3p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10397/Upstream/1111363; hsa-mir-103a-1/Downstream/1804659;
Nearest TSS
ENST00000502646/Upstream/4643; ENST00000518919/Downstream/22911;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/4865, chr5-CpG: 43/Downstream/439169
Upstream sequence
cctgcctcagcctcttgagtagctgggattacaggcatgcgccaccacacctggctaattttgtattttaagtagagacagggattctccatgttggtca
Downstream sequence
ggctggtcttgaactcctgacctcaggtgatcagccagccttggcttcccaaagtactgggattacaggcatgagccaccgtgcccagcaactgggacag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate