Basic Information
VIS ID
TVIS44031080
Fusion event
HTLV-1-STXBP5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
147643401/147280572 (Hg38)
End
147643401/147280572 (Hg38)
Orient
-
Location type
Intronic
Target gene
STXBP5
miRNAs that regulate target gene
hsa-mir-21-5p
Nearest miRNA
hsa-mir-10398/Upstream/6596689; hsa-mir-1202/Downstream/3822103;
Nearest TSS
ENST00000381078/Upstream/75958; ENST00000367475/Downstream/46601;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/75860, chr6-CpG: 23/Downstream/126374
Upstream sequence
aaattgagaaataaattttgtatttataattgttaagtattttgatttgaaggaagttccacaagactctatgaacatattatacttcatcaaacttttc
Downstream sequence
ccctttagttttagcatctgttgatgtttcttagctgaattcactattactgtgatggttgccaaataatgattGTCTAGCTGGTCTTAATCTTTTTTTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate