Basic Information
VIS ID
TVIS44031088
Fusion event
HTLV-1-PKHD1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
51696425/51723668 (Hg38)
End
51696425/51723668 (Hg38)
Orient
+
Location type
Intronic
Target gene
PKHD1
miRNAs that regulate target gene
hsa-mir-759 ; hsa-mir-892c-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4727-3p ; hsa-mir-6826-5p ; hsa-mir-1296-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-552-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-4323 ; hsa-mir-4482-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-9-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-6504-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-4700-3p ; hsa-mir-892c-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-891b ; hsa-mir-574-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p
Nearest miRNA
hsa-mir-10398/Upstream/6525898; hsa-mir-10524/Downstream/420681;
Nearest TSS
ENST00000381078/Upstream/101847; ENST00000340057/Downstream/363942;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/872950, chr6-CpG: 54/Downstream/560683
Upstream sequence
TTCAAAGTGTGATAACACAACTAACTCCAAAACAGGAAGTGAAAACAAGATTAAAATAAAAATTGATGGTGAAATGTTATTTTGGACTAGTTATGTGTGG
Downstream sequence
GTTACCAAGAGTGATTTAAGATATTTTCTTTCCTCTTTCTCCATCTCTCTCAAAAGGAGAAAGGCGAAAGAAAACATCTTAAATCACCAGGTCTGGGCTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate